If you re running a windows operating system you will want to set up some standard anti-virus exclusions. Most people ust install their A/V product and don’t configure it leading to complaints around slowing down of the computer or things just plain not working. A classing is the secedit.sdb fil becoming corrupted and preventing GPO’s being sunsequently applied.
Microsoft (and Citrix) list their standard exclusions as below.
AV on ALL windows computers
http://support.microsoft.com/kb/822158
Additional AV exclusions on servers running MS Server products
http://support.microsoft.com/kb/943556
Citrix AV exclusions
http://support.citrix.com/article/CTX127030
AppSense Exclusions
http://appsensebigot.blogspot.co.uk/2012/03/antivirus-exclusions-for-appsense.html
Philip Flint 