If you re running a windows operating system you will want to set up some standard anti-virus exclusions. Most people ust install their A/V product and don’t configure it leading to complaints around slowing down of the computer or things just plain not working. A classing is the secedit.sdb fil becoming corrupted and preventing GPO’s being sunsequently applied.
Microsoft (and Citrix) list their standard exclusions as below.
AV on ALL windows computers
Additional AV exclusions on servers running MS Server products
Citrix AV exclusions